Utilizing a range of instruments, including UPLCs, GCs, ICP, TOF-MS, GCP, and NMR, we conduct routine analysis for established processes and develop new methods for analyzing molecules from emerging chemistries.

Synthesis pathways are developed to advance the production of new, promising molecules. This includes validating production feasibility, assessing cost and time impacts, and refining chemical properties based on application screenings to achieve optimal conditions for commercial production.

Genetic engineering techniques are employed to fine-tune microbial strains, optimizing their ability to produce enzyme catalysts used in our manufacturing processes.

Leveraging artificial intelligence and machine learning, we fine-tune complex chemical processes, optimize reaction yields, and improve product quality. This technology accelerates directed enzyme evolution by predicting the functional effects of multiple mutations and facilitates the design of DNA libraries for high-throughput screening. It also expedites the design of metal catalysts and enhances manufacturing operations.

Rigorous quality control measures are put in place to ensure the consistency, purity, and excellence of our final products.

Along the way, innovative products and applications for current and future chemistries are created and tested. This involves strategically orchestrating market research, ideation, prototyping, and testing to bridge the gap between innovative ideas and successful product commercialization.

After new chemistries are synthesized, we translate them into scaleable engineering designs. This involves the design and scale up of new processes that are robust, clean, and enable high yields.

The engineered enzymes used in our manufacturing process are produced at our Bioflex® Senior fermentation plant. Named for its equipment flexibility, Bioflex can produce both intracellular and extracellular enzymes in bacteria, yeast, and filamentous fungi, enabling rapid and cost-effective scaling of new enzymes and processes.

Enzymes and metal catalysts are tested in our pilot plant to improve our understanding of the chemistry and kinetics of reactions on a commercial scale. We identify and address limitations observed at the bench-scale, ensuring successful transfer of information, learnings, and data to engineering and operations across various scales.