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A New Way to
Manufacture Chemicals

High Yield, Low Impact

Our proprietary technology platform optimizes critical steps in the production process, reducing inefficiencies and delivering better performance and value for our customers.

It all starts with our feedstock.

Circular Feedstocks Read More

Our process starts with simple, abundant, and inexpensive bio-based feedstocks. Dextrose, water, and compressed air is continuously pumped into our enzyme oxidation reactor where our engineered enzymes begin the conversion process.

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Enzymes begin the highly efficient conversion process.

Engineered Enzymes Read More

The use of computational design, rational design, and AI optimizes our enzymes, resulting in superior efficiency and sustainability across a diverse range of molecules. The development process includes generating AI-filtered smart libraries, high-throughput screening of thousands of enzyme variants, and fermentation to scale up production in large bioreactors. These engineered enzymes drive highly efficient, cell-free reactions at room temperature with low energy input.

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Metal catalysts optimize throughput.

Heterogeneous Metal Catalysts Read More

The use of proprietary metal catalysts significantly enhance the efficiency of our process. We begin by synthesizing, analyzing, and characterizing each catalyst, followed by precise adjustments in parameters for optimal performance. Once a suitable catalyst is identified, it undergoes rigorous testing in our reactors to ensure its suitability for commercial use.

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The result— high performing, cost competitive, sustainable products.

Product Read More

By iterating advanced reaction technologies with modern separations techniques, we consistently achieve integrated yields of over 95%, and in some cases near unity. By efficiently converting our raw materials directly into valuable products, we bypass the inefficiencies of traditional methods with little to no harmful emissions and no hazardous waste.

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Optimizing every step of the way

Solugen’s world-class research and development team boasts a range of advanced technical capabilities that allows us to refine and optimize every aspect of the manufacturing process.

Our Capabilities

Analytical Chemistry

Utilizing a range of instruments, including UPLCs, GCs, ICP, TOF-MS, GCP, and NMR, we conduct routine analysis for established processes and develop new methods for analyzing molecules from emerging chemistries.

Chemical Synthesis

Synthesis pathways are developed to advance the production of new, promising molecules. This includes validating production feasibility, assessing cost and time impacts, and refining chemical properties based on application screenings to achieve optimal conditions for commercial production.

Strain Engineering

Genetic engineering techniques are employed to fine-tune microbial strains, optimizing their ability to produce enzyme catalysts used in our manufacturing processes.

AI/Machine Learning

Leveraging artificial intelligence and machine learning, we fine-tune complex chemical processes, optimize reaction yields, and improve product quality. This technology accelerates directed enzyme evolution by predicting the functional effects of multiple mutations and facilitates the design of DNA libraries for high-throughput screening. It also expedites the design of metal catalysts and enhances manufacturing operations.

Quality Control and Assurance

Rigorous quality control measures are put in place to ensure the consistency, purity, and excellence of our final products.

Product Development

Along the way, innovative products and applications for current and future chemistries are created and tested. This involves strategically orchestrating market research, ideation, prototyping, and testing to bridge the gap between innovative ideas and successful product commercialization.

Process Development

After new chemistries are synthesized, we translate them into scaleable engineering designs. This involves the design and scale up of new processes that are robust, clean, and enable high yields.

Fermentation

The engineered enzymes used in our manufacturing process are produced at our Bioflex® Senior fermentation plant. Named for its equipment flexibility, Bioflex can produce both intracellular and extracellular enzymes in bacteria, yeast, and filamentous fungi, enabling rapid and cost-effective scaling of new enzymes and processes.

Pilot Plant

Enzymes and metal catalysts are tested in our pilot plant to improve our understanding of the chemistry and kinetics of reactions on a commercial scale. We identify and address limitations observed at the bench-scale, ensuring successful transfer of information, learnings, and data to engineering and operations across various scales.

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